Clinical manifestations and complications of preeclampsia and eclampsia in populations residing at high altitudes and very high altitudes: A scoping review.

INTRODUCTION: Preeclampsia and eclampsia are conditions that affect gestation, characterized by high blood pressure and direct organ damage, while geographical altitude directly affects cardiovascular physiology. The aim of this review is to identify the clinical manifestations and complications of preeclampsia in pregnant women at high and very high altitudes. METHODS: A scoping review was conducted to assess the objective. A systematic search was performed on Pubmed, Web of Science, Embase, Scopus, Scielo, and Lilacs. Studies including pregnant women with preeclampsia or eclampsia at high altitudes and very high altitudes were included, excluding non-citable documents. Results were summarized in tables based on bibliographic data, methodological aspects, and key findings. RESULTS: Eight documents meeting the inclusion and exclusion criteria were obtained. Seven studies focused on populations in Latin America, with the highest geographical altitude being 4380 m above sea level in the city of Cerro de Pasco, Peru. One report suggests a higher admission rate to the Intensive Care Unit and a higher frequency of HELLP syndrome. Functional cardiovascular changes were also observed. CONCLUSIONS: There are few studies directly evaluating pregnant populations at high altitudes and very high altitudes experiencing preeclampsia and eclampsia. Complications may be more frequent at high altitudes and very high altitudes with clinically unobservable cardiovascular changes.

substance use and recidivism of intimate partner violence in Peru: A cross-sectional study.

Background: Intimate Partner Violence (IPV) carries significant global burden, with approximately 27% of women who have ever had a partner experiencing IPV. Additionally, substance use (alcohol and drugs) is often associated with aggressive attitudes and serves as a risk factor for IPV. Objective: Determine the association between substance use and the recurrence of IPV in the Peruvian population in 2022. Methods: A cross-sectional study was conducted using public data from the Ministry of Women, employing regression based on generalized linear models to calculate crude and adjusted Odds Ratios. Results: A total of 65,290 cases of IPV were analyzed, the results revealed that 93.70% of the reports were cases of recidivism. A relationship was identified between substance use and IPV, with an Odds Ratio of 2.24 for the perpetrator's alcohol consumption and an Odds Ratio of 2.33 for drug use. Conclusion: Based on these findings, it can be concluded that a relationship exists between substance use and IPV, and national strategies should incorporate proper monitoring after the initial report of violence, as well as effective control of substance use among perpetrators.

Evolution and differences of suicide rates in Peru by gender and department, 2017-2019.

INTRODUCTION: Annual suicide rates are increasingly notably worldwide due to various accompanying risk factors. The objective of this study is to know the suicide mortality rates and their distribution between the years 2017 and 2019. METHODS: The national death registries of the Ministry of Health of Peru were analysed, calculating the regional death rates from suicides adjusted for age and gender using the standardisation recommended by the World Health Organization. RESULTS: A total of 1666 cases of suicide were identified (69.3% males); the age group with the highest frequency was that of 20-29 years (27.8%); the mean age at suicide was higher in males (37.49±18.96 vs. 27.86±15.42; P<.001). Hanging was the most common suicide method among both males (58.87%) and females (48.14%). For males, hanging was followed by poisoning (22.6%) and firearms (4.59%); for females, by poisoning (38.75%) and firearms (0.59%). The suicide rate increased from 2017 (1.44/100,000 inhabitants) to 2019 (1.95). The highest rates were identified in the departments of Arequipa, Moquegua and Tacna. CONCLUSIONS: In recent years, there has been an increase in the number of suicide cases and the rates by department, with the highest number of cases reported in males. Males tend to use more violent suicide methods. The risk factors in the vulnerable populations that were identified in this study need to be known.

Evolución y diferencias en las tasas de suicidio en Perú por sexo y por departamentos, 2017-2019

Introducción: Cada ano, los casos de suicidio vienen en notable aumento en todo el mundo por diversos factores de riesgo. El objetivo de este estudio es conocer las tasas de mortalidad por suicidios y su distribución entre los años 2017 y 2019. Métodos: Se analizaron los registros nacionales del Sistema Nacional de defunciones del Ministerio de Salud del Perú. Se calcularon las tasas regionales de mortalidad por suicidios ajustadas por edad y sexo mediante la estandarización recomendada por la Organización Mundial de la Salud. Resultados: Se identificaron 1.666 casos de suicidio (el 69,3% varones); el grupo etario con mayor frecuencia fue el de 20 a 29 años (27,8%); la media de edad al suicidio fue mayor en los varones (37,49 ± 18,96 frente a 27,86 ± 15,42; p< 0,001). El ahorcamiento fue el método de suicidio más prevalente entre los varones (58,87%) y las mujeres (48,14%). En el caso de los varones, los demás métodos fueron envenenamiento (22,6%) y armas de fuego (4,59%); en el de las mujeres, envenenamiento (38,75%) y uso de armas de fuego (0,59%). La tasa de suicidio aumento de 2017 (1,44 muertes/100.000 hab.) a 2019 (1,95). Las mayores tasas se identificaron en los departamentos de Arequipa, Moquegua y Tacna. Conclusiones: En los últimos años ha habido un aumento en el número de casos de suicidio y en las tasas por departamento; el mayor número de casos reportados se da en los varones, que tienden a utilizar métodos de suicidio más violentos. Se requiere conocer los factores de riesgo en las poblaciones vulnerables identificadas en este estudio.

Introduction: Annual suicide rates are increasingly notably worldwide due to various accompanying risk factors. The objective of this study is to know the suicide mortality rates and their distribution between the years 2017 and 2019. Methods: The national death registries of the Ministry of Health of Peru were analysed, calculating the regional death rates from suicides adjusted for age and gender using the standardisation recommended by the World Health Organization. Results: A total of 1,666 cases of suicide were identified (69.3% males); the age group with the highest frequency was that of 20 to 29 years (27.8%); the mean age at suicide was higher in males (37.49 ± 18.96 vs. 27.86 ± 15.42; p < 0.001). Hanging was the most common suicide method among both males (58.87%) and females (48.14%). For males, hanging was followed by poisoning (22.6%) and firearms (4.59%); for females, by poisoning (38.75%) and firearms (0.59%). The suicide rate increased from 2017 (1.44/100,000 inhabitants) to 2019 (1.95). The highest rates were identified in the departments of Arequipa, Moquegua and Tacna. Conclusions: In recent years, there has been an increase in the number of suicide cases and the rates by department, with the highest number of cases reported in males. Males tend to use more violent suicide methods. The risk factors in the vulnerable populations that were identified in this study need to be known.

Factores asociados al requerimiento de rehabilitación física en los peatones sobrevivientes de atropello en Perú, 2016 - 2021

Introducción. Los accidentes de tránsito (AT) son un problema de salud pública a nivel mundial, se estiman 1,3 millones de muertes anuales, y en los sobrevivientes deja secuelas traumáticas que pueden disminuir la calidad de vida. De las víctimas, los peatones lesionados representan el 22%. El objetivo del presente estudio fue determinar los factores asociados al requerimiento de rehabilitación física de los peatones lesionados por algún AT en el territorio peruano. Métodos. Se realizó un estudio observacional de corte transversal con los datos secundarios brindados por el Centro Nacional de Epidemiología, Prevención y Control de Enfermedades (CDC Perú) por medio de fichas epidemiológicas. Resultados. Se analizaron 14 186 registros que involucran a peatones lesionados por atropellamiento en carretera por algún vehículo motorizado entre el 2016 y el 2021. El 87,89% de las víctimas no requirieron rehabilitación posterior al suceso. Existe una mayor probabilidad de rehabilitación si el lesionado tiene una mayor edad y si la hora del accidente fue entre las 00:00 y 05:59 horas del día. Existe una menor probabilidad de rehabilitación si el accidente lo ocasiona un motocarro. Conclusiones. Existe una gran cantidad de accidentados jóvenes y adultos, sin embargo, la edad mayor se comporta como un factor asociado a la necesidad de rehabilitación, así mismo, el tipo de carretera y el tipo de vehículo causante influyen en el desenlace de la víctima.

Introduction. Traffic accidents (TA) are a public health problem worldwide, with an estimated 1.3 million deaths per year from collisions and leaves traumatic sequels in the survivors. Of the total number of victims affected in an AT, injured pedestrians represent 22%. The objective of this study was to determine the factors associated with the requirement of physical rehabilitation of pedestrians injured by any TA in the Peruvian territory. Methods. An observational cross-sectional study was carried out with the data provided by the National Center for Epidemiology, Prevention, and Control of Diseases (CDC Peru) through epidemiological records. A regression analysis was performed, and prevalence ratios (PR) were reported, having the rehabilitation requirement as a dependent variable. Results. A total of 14,186 records of pedestrians injured by being hit by a motor vehicle on the road between 2016 and 2021 were analyzed. 87.89% of the victims did not require post-event rehabilitation. There is a greater probability of rehabilitation if the injured person is older and if the time of the accident occurred between 00:00 and 05:59 hours of the day. There is a lower probability of rehabilitation if the accident is caused by a minor motor vehicle. Conclusions. Many young people and adults are injured; however, older age is a factor associated with the need for rehabilitation, likewise, the type of road and the type of vehicle responsible influence the outcome of the victim.

Characteristics and Factors Associated With Age and Gender Among Peruvian Children and Adolescents Who Are Victims of Sexual Violence.

Objectives. To identify the characteristics and factors associated with the gender and age of victims and aggressors. Methodology. A cross-sectional study was conducted using data from the Ministry of Women and Vulnerable Populations. Linear regression and Poisson regression were used to determine ß coefficients and prevalence ratios (PR) between general characteristics and victim gender and age. Results. A total of 6929 records were analyzed. Factors associated with victim gender included urban area of residence (P < .001), alcohol consumption (P < .001). Factors associated with older victim age were being female (ß = 3.08) and not being related to the aggressor (ß = 1.73). Aggressors were older if they were the father (ß = 7.58) or stepfather (ß = 5.08), and if the rape had occurred previously (ß = 6.11). Conclusions. There are factors directly associated with the gender and age of the victim. Strategies to prevent sexual assaults, especially within the family context, should be strengthened.

Femicides and Victim's age-Associated Factors in Peru.

Background. Femicides are an increasing social problem worldwide. In this study, we aim to describe the trend of femicides in the prepandemic decade and characterize the femicide victims and their perpetrators. Methods. We assessed the trend of femicides in Peru during 2010-2019 and performed a cross-sectional study to analyze the femicides reported in 2019 using open data. Results. We analyzed 166 femicides reported in 24/25 regions of Peru in 2019 and calculated a yearly incidence of 1.01 femicides per 100,000 women. This incidence level represents an increase of 38% compared to the mean annual incidence from 2010 to 2018 (0.74 femicides per 100,000 women). Most femicides occurred in urban areas (64%), through strangling/asphyxiation (25.9%), stabbing (23%), and shooting (16%). Most victims were mothers (61%) 30 years old or over (51%). Most perpetrators have had a partner history with their victims (69%), 30 years old or over (62%), employed (57%), and consumed enablers (51%). Our regression analysis observed that the victim's age was associated with the perpetrator's age and partner history. Conclusions. Femicides are endemic in Peru, and the main characteristics of the victims and their perpetrators offer opportunities for tackling this social problem in Peru and similar low- to middle-income countries.

Producción científica en Scopus de los institutos de salud especializados públicos de Perú, 2010-2022

Objetivo: Evaluar la producción científica de los institutos de salud de Perú en Scopus, 2010-2022. Métodos : Estudio bibliométrico realizado en Scopus durante septiembre del 2022, en 14 institutos de salud especializados públicos de Perú. Incluimos estudios originales que tuvieran al menos un autor de alguno de los institutos. Resultados : Los institutos incluidos publicaron entre 0 y 347 artículos originales (H-index entre 0 y 51). Los institutos de la ciudad de Lima fueron los que tuvieron mayor producción. En los siete institutos con mayor producción, el porcentaje de artículos con autor corresponsal del instituto evaluado varió entre 22.3% y 36.7%, y el porcentaje de estudios que declararon ser financiados por el instituto varió entre 0% y 11.6%. Conclusión : La producción científica de los institutos evaluados fue heterogénea, a predominio de aquellos ubicados en Lima. Los institutos raramente participaron en el financiamiento de los estudios publicados.

Objective: To evaluate the scientific production of Peruvian health institutes in Scopus, 2010-2022. Methods: We conducted a Bibliometric study in Scopus during September 2022, in 14 public specialized health institutes of Peru. We included original studies with at least one author from one of the institutes. Results: The institutes included published between 0 and 347 original articles (H-index between 0 and 51). The institutes in the city of Lima were the ones with the highest production. In the seven institutes with the highest production, the percentage of articles with a corresponding author from the institute evaluated ranged from 22.3% to 36.7%, and the percentage of studies that reported being financed by the institute ranged from 0% to 11.6%. Conclusion: The scientific production of the evaluated institutes was heterogeneous, with a predominance of those located in Lima. The institutes rarely participated in the financing of the published studies.

Sociodemographic Factors Associated with Social Tolerance for Intimate Partner Violence in Peru: Evidence from the National Survey of Social Relations, 2019.

Our objective was to determine the factors associated with social tolerance for intimate partner violence (IPV) in the Peruvian population. A population-based cross-sectional study was conducted. Data from the 2019 National Survey of Social Relations (ENARES) of Peru were used. This survey collected data from a total of 1,026 Peruvians aged 18 years and older. Multilevel linear regression models were performed to evaluate the factors associated with a standardized index of social tolerance for IPV. Likewise, a stratified analysis was performed according to sex. Being older (ß = .01; 95% confidence interval [CI]: .01-.01) and living outside the capital (ß = 0.24; 95% CI: .07-0.41) were associated with greater social tolerance for IPV. On the other hand, being female (ß = -0.26; 95% CI: -0.36 to -0.17) and having a higher educational level were associated with lower tolerance. In the stratified analysis by sex, in both men and women, being older and having a higher level of education were associated with higher and lower tolerance for IPV, respectively. On the other hand, living outside the capital was associated with greater tolerance only in men. In Peru, older people and those living outside the capital showed greater acceptance of IPV, while women and those with higher levels of education expressed rejection of IPV.

Embarazo en adolescentes. Análisis de natalidad en Perú y su relación con el Índice de Desarrollo Humano / Teenage pregnancy. Analysis of birth rate in Peru and its relationship with the Human Development Index

Resumen: OBJETIVO: Determinar la frecuencia de embarazos mediante la tasa de nacidos vivos en el grupo etario de 15 a 19 años y su asociación con el Índice de Desarrollo Humano (2016 a 2021). MATERIALES Y MÉTODOS: Estudio observacional, ecológico, exploratorio y correlacional efectuado con base en la información del Sistema de Registro del Certificado de Nacido Vivo en Línea y el Índice de Desarrollo Humano, que son datos por departamento, provincias y municipios. Se incluyeron todas las mujeres residentes en Perú con un recién nacido entre 2016 y 2021. Los datos registrados fueron: total de recién nacidos por departamento, región, provincia y distrito, divididos por grupos etarios de 15 a 19 años. Para el análisis de los datos se utilizaron regresión lineal y correlación de Pearson. RESULTADOS: En el periodo de estudio se registraron 2,843,903 nacimientos de los que 324,654 (11.41%) correspondieron a mujeres menores de 20 años. En el 2017 se registró la más alta cantidad de nacimientos en este grupo etario (n = 58,841). En 2016 el porcentaje más alto de nacimientos de hijos de adolescentes fue de 12.36% y el más bajo (10.51%) se registró en el 2020. CONCLUSIÓN: El porcentaje de adolescentes embarazadas disminuyó levemente en los últimos años, aunque hubo un ligero aumento en el 2021, sobre todo en la región de la selva, que es la de mayor proporción en comparación con las otras. El índice de desarrollo humano provincial y municipal está inversamente relacionado con la proporción de embarazos en adolescentes.

Abstract OBJECTIVE: To determine the frequency of pregnancies through the live birth rate in the 15-19 age group and its association with the Human Development Index (2016 to 2021). MATERIALS AND METHODS: Observational, ecological, exploratory, and correlational study carried out based on information from the Online Live Birth Certificate Registration System and the Human Development Index, which are data by department, provinces and municipalities. All women residing in Peru with a newborn between 2016 and 2021 were included. The data recorded were total newborns by department, region, province and district, divided by age groups from 15 to 19 years. Linear regression and Pearson correlation were used for data analysis. RESULTS: In the study period, 2,843,903 births were registered, of which 324,654 (11.41%) corresponded to women under 20 years of age. In 2017, the highest number of births was recorded in this age group (n = 58,841). In 2016, the highest percentage of births to teenagers was 12.36% and the lowest (10.51%) was recorded in 2020. CONCLUSION: The percentage of pregnant adolescents decreased slightly in recent years, although there was a slight increase in 2021, especially in the jungle region, which has the highest proportion compared to the others. The provincial and municipal human development index is inversely related to the proportion of teenage pregnancy.

Tendencia y distribución regional de la mortalidad materna en el Perú: 2015-2019 / Maternal mortality trend and regional distribution in Peru: 2015-2019

Resumen OBJETIVO: Describir la razón de mortalidad materna para 25 regiones peruanas entre 2015 y 2019, conocer su tendencia y algunos factores determinantes. MATERIALES Y MÉTODOS: Estudio retrospectivo y observacional efectuado con base en los casos de muerte materna registrados en el Repositorio Único Nacional de Información de Salud (REUNIS) del Perú de 2015 a 2019. Los datos se analizaron mediante la razón de mortalidad materna por 100,000 nacidos vivos. RESULTADOS: Se observó una tendencia de mortalidad materna descendente (415 casos en 2015 a 302, en 2019) y una razón de mortalidad materna de 76.34. La edad media fue 29.2 años (± 7.8). Las razones de mortalidad materna más altas se observaron en mujeres de la selva peruana (195.1), con parto domiciliario (1754.8) y atendidas en instituciones del primer nivel de atención (113.5). La región con más casos de muerte materna fue la Sierra peruana (37.61%). CONCLUSIÓN: En el periodo de estudio la razón de mortalidad materna en el Perú tuvo una ligera disminución, con una tendencia descendente. Solo 9 regiones lograron una razón de mortalidad materna menor de 70.

Abstract OBJECTIVE: Describe the trend and regional distribution of maternal mortality in Peru between 2015 and 2019. MATERIALS AND METHODS: A retrospective observational study was carried out based on the cases of maternal death (MM) registered in the National Repository of Health Information (REUNIS) of Peru between 2015 and 2019. The data were analyzed using the maternal mortality ratio (MMR) per 100,000 live births (NV). RESULTS: A descending maternal mortality trend was observed (415 cases in 2015 to 302 in 2019) and a MMR of 76.34. The mean age was 29.2 years (± 7.8). The highest MMRs were observed in women from the Peruvian jungle (195.1), with home birth (1754.8), and attended in institutions of the first level of care (113.5). The region with the most cases of MM was the Peruvian Sierra (37.61%). CONCLUSION: In the study period, the MMR in Peru had a slight decrease, with a downward trend. Only 9 regions achieved an MMR <70.

Evolution and Differences of Suicide Rates in Peru by Gender and Department, 2017-2019. / Evolución y diferencias en las tasas de suicidio en Perú por sexo y por departamentos, 2017-2019.

INTRODUCTION: Annual suicide rates are increasingly notably worldwide due to various accompanying risk factors. The objective of this study is to know the suicide mortality rates and their distribution between the years 2017 and 2019. METHODS: The national death registries of the Ministry of Health of Peru were analysed, calculating the regional death rates from suicides adjusted for age and gender using the standardisation recommended by the World Health Organization. RESULTS: A total of 1,666 cases of suicide were identified (69.3% males); the age group with the highest frequency was that of 20 to 29 years (27.8%); the mean age at suicide was higher in males (37.49±18.96 vs. 27.86±15.42; p<0.001). Hanging was the most common suicide method among both males (58.87%) and females (48.14%). For males, hanging was followed by poisoning (22.6%) and firearms (4.59%); for females, by poisoning (38.75%) and firearms (0.59%). The suicide rate increased from 2017 (1.44/100,000 inhabitants) to 2019 (1.95). The highest rates were identified in the departments of Arequipa, Moquegua and Tacna. CONCLUSIONS: In recent years, there has been an increase in the number of suicide cases and the rates by department, with the highest number of cases reported in males. Males tend to use more violent suicide methods. The risk factors in the vulnerable populations that were identified in this study need to be known.